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Invitrogen
RGS20 Polyclonal Antibody
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FIGURE: 1 / 4
RGS20 Antibody (PA5-104093) in ICC/IF
Immunocytochemistry analysis of RGS20 in A549 cells. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 minutes at 25°C. Samples were incubated with RGS20 polyclonal antibody (Product # PA5-104093) and mouse anti-beta tubulin antibody for 1 hour at 37°C. An AlexaFluor594 conjugated goat anti-rabbit IgG (Red) and an AlexaFluor488 conjugated goat anti-mouse IgG (Green) were used as the secondary antibodies. The nuclear counter stain is DAPI (blue).
Product Details
PA5-104093
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RGS20(Accession O76081), corresponding to amino acid residues G143-A193.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853421
Product Specific Information
Antibody detects endogenous levels of total RGS20.
Target Information
Regulator of G protein signaling (RGS) proteins are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins are GTPase-activating proteins for Gi (see GNAI1; MIM 139310) and Gq (see GNAQ; MIM 600998) class G-alpha proteins. They accelerate transit through the cycle of GTP binding and hydrolysis and thereby accelerate signaling kinetics and termination.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G(z)GAP; Gz-selective GTPase-activating protein; Regulator of G-protein signaling 20; regulator of G-protein signaling 20 variant 2; Regulator of G-protein signaling Z1; regulator of G-protein signalling 20; Regulator of Gz-selective protein signaling 1; RGS20
Gene Aliases: 2900073E09Rik; g(z)GAP; gz-GAP; RGS20; RGSZ1; ZGAP1
UniProt ID: (Human) O76081, (Mouse) Q9QZB1
Entrez Gene ID: (Human) 8601, (Mouse) 58175
G-protein coupled receptor signaling pathway
negative regulation of signal transduction
termination of G-protein coupled receptor signaling pathway
positive regulation of GTPase activity
regulation of transcription, DNA-templated
cell death
regulation of G-protein coupled receptor protein signaling pathway
dorsal/ventral axis specification
cell differentiation
regulation of catenin import into nucleus
cellular response to organic cyclic compound
negative regulation of canonical Wnt signaling pathway
Wnt signaling pathway involved in somitogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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