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Product Details
PA5-20861
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
An 18 amino acid peptide from near the center of human RHBDD2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_11156200
Product Specific Information
A suggested positive control is rat lung tissue lysate.
PA5-20861 can be used with blocking peptide PEP-0975.
Target Information
The Rhomboid family of proteins is made up of several widely conserved polytopic membrane serine proteases that play roles in growth and development. Little is known about the role of RHBDD2. Its overexpression in breast carcinoma appears to be an indicator of poor prognosis and may play a role in breast cancer progression. The related proteins RHBDD1 and RHBDD3 are both involved in the regulation of apoptosis, suggesting that RHBDD2 may also be involved in the modulation of apoptotic activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: H_RG122E10.2a; H_RG122E10.2b; Rhomboid domain-containing protein 2; rhomboid, veinlet-like 7; Rhomboid-like protein 7; upregulated during skeletal muscle growth 1; WUGSC:H_RG122E10.2a; WUGSC:H_RG122E10.2b
Gene Aliases: 0610011L13Rik; AI480532; NPD007; RHBDD2; RHBDL7; Usmg1
UniProt ID: (Human) Q6NTF9, (Mouse) Q8VEK2
Entrez Gene ID: (Human) 57414, (Rat) 360793, (Mouse) 215160
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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