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Invitrogen
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Immunogen sequence: HRLPRRRKRE SVAKMSFRAA AALMKGRSVR DGTFRRAQRR SFTPASFLEE DTTDFPDELD TSFFAREGIL HEELSTYPDE VFESPSEAAL KDWEKAPEQA DLTGGALDRS ELERSHLMLP LERGWRKQKE GAAAPQPKVR LRQEVVSTAG PRRGQRIAVP VRKLFAREKR PYGLGMVGRL TNRTYRKRID SFVKRQIEDM D
RHBDF1 is a seven-transmembrane protein with a long N-terminal cytoplasmic extension that comprises half of the polypeptide sequence, and is found in the endoplasmic reticulum and Golgi, but not on the cell surface. RHBDF1 has a pivotal role in sustaining growth signals in epithelial cancer cells and thus may serve as a therapeutic target for treating epithelial cancers.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: epidermal growth factor receptor related sequence; Epidermal growth factor receptor-related protein; FLJ2235; FLJ22357; gene -89; gene -90; Inactive rhomboid protein 1; iRhom1; rhomboid family 1; Rhomboid family member 1
Gene Aliases: C16ORF8; Dist; Dist1; Egfr-rs; Irhom1; Kiaa4242; mKIAA4242; Rhbdf1
UniProt ID: (Mouse) Q6PIX5, (Rat) Q499S9
Entrez Gene ID: (Mouse) 13650, (Rat) 303008
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