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Proteintech
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Immunogen sequence: KNPAYLKSV SLQEPRSRWQ ESSEKRPGFR RQASLSQSIR KGAAQWFGVS GDWEGQRQQW QRRSLHHCSM RYGRLKASCQ RDLELPSQEA PSFQGTESPK PCKMPKIVDP LARGRAFRHP EEMDRPHALH PPLTPGVLSL TSFTSVRSGY SHLPRRKRMS VAHMSLQAAA ALLKGRSVLD ATGQRCRVVK RSFAFPSFLE EDVVDGADTF DSSFFSKEEM SSMPDDVFES PPLSASYFRG IPHSASPVSP DGVQIPLKEY GRAPVPGPRR GKRIASKVKH FAFDRKKRHY GLGVVGNWLN RSYRRSISST VQRQLESFDS H (81-400 aa encoded by BC016034)
Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Inactive rhomboid protein 2; iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6
Gene Aliases: IRHOM2; RHBDF2; RHBDL5; RHBDL6; TEC; TOC; TOCG
UniProt ID: (Human) Q6PJF5
Entrez Gene ID: (Human) 79651
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