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Proteintech
RILP Polyclonal Antibody
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Product Details
13574-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RILP Fusion Protein Ag4472 (101-401 aa encoded by BC031621)
Conjugate
Form
Liquid
Concentration
0.58 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: ELRAGPQEE RALLRQLKEV TDRQRDELRA HNRDLRQRGQ ETEALQEQLQ RLLLVNAELR HKLAAMQTQL RAAQDRERER QQPGEAATPQ AKERARGQAG RPGHQHGQEP EWATAGAGAP GNPEDPAEAA QQLGRPSEAG QCRFSREEFE QILQERNELK AKVFLLKEEL AYFQRELLTD HRVPGLLLEA MKVAVRKQRK KIKAKMLGTP EEAESSEDEA GPWILLSDDK GDHPPPPESK IQSFFGLWYR GKAESSEDET SSPAPSKLGG EEEAQPQSPA PDPPCSALHE HLCLGASAAP EA (101-401 aa encoded by BC031621)
Target Information
The Rab interacting lysosomal protein (RILP) is lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. It is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic. Overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell suggesting that RILP may also be involved in the regulation of lysosomal morphology. Other evidence suggests that RILP may play a role in the biogenesis of multivesicular bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Rab-interacting lysosomal protein
Gene Aliases: PP10141; RILP
UniProt ID: (Human) Q96NA2
Entrez Gene ID: (Human) 83547
endosome to lysosome transport
regulation of multivesicular body size
protein transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
endosome transport via multivesicular body sorting pathway
negative regulation of protein catabolic process
early endosome to late endosome transport
positive regulation of protein catabolic process
intralumenal vesicle formation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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