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Invitrogen
RILP Polyclonal Antibody
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Product Details
PA5-34357
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
An 18 amino acid synthetic peptide near the center of human RILP
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.02% sodium azide
Storage conditions
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2551709
Product Specific Information
A suggested positive control is A-20 cell lysate.
PA5-34357 can be used with blocking peptide PEP-1400.
Target Information
The Rab interacting lysosomal protein (RILP) is lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. It is thought that RILP is a downstream effector of RAB7 and both proteins act together in the regulation of late endocytic traffic. Overexpression of RILP caused enlarged lysosomes that are more centrally located in the cell suggesting that RILP may also be involved in the regulation of lysosomal morphology. Other evidence suggests that RILP may play a role in the biogenesis of multivesicular bodies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Rab-interacting lysosomal protein
Gene Aliases: AI835553; Gm857; PP10141; RILP
UniProt ID: (Human) Q96NA2, (Mouse) Q5ND29
Entrez Gene ID: (Human) 83547, (Mouse) 280408
endosome to lysosome transport
regulation of multivesicular body size
protein transport
antigen processing and presentation of exogenous peptide antigen via MHC class II
endosome transport via multivesicular body sorting pathway
negative regulation of protein catabolic process
early endosome to late endosome transport
positive regulation of protein catabolic process
intralumenal vesicle formation
transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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