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Abnova
RILPL1 Polyclonal Antibody, MaxPab™
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Product Details
H00353116-B01P
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Mouse
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RILPL1 (NP_847884.1, 1 a.a. approximately 362 a.a) full-length human protein.
Conjugate
Form
Liquid
Concentration
0.5-1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MDVYDIASLV GHEFERVIDQ HGCEAIARLM PKVVRVLEIL EVLVSRHHVA PELDELRLEL DRLRLERMDR IEKERKHQKE LELVEDVWRG EAQDLLSQIA QLQEENKQLM TNLSHKDVNF SEEEFQKHEG MSERERQVMK KLKEVVDKQR DEIRAKDREL GLKNEDVEAL QQQQTRLMKI NHDLRHRVTV VEAQGKALIE QKVELEADLQ TKEQEMGSLR AELGKLRERL QGEHSQNGEE EPETEPVGEE SISDAEKVAM DLKDPNRPRF TLQELRDVLH ERNELKSKVF LLQEELAYYK SEEMEEENRI PQPPPIAHPR TSPQPESGIK RLIFTAIMPM VAAGLIIDDP TLQPVRRLVS LV
Target Information
Plays a role in the regulation of cell shape and polarity. Plays a role in cellular protein transport, including protein transport away from primary cilia. Neuroprotective protein, which acts by sequestring GAPDH in the cytosol and prevent the apoptotic function of GAPDH in the nucleus. Competes with SIAH1 for binding GAPDH. Does not regulate lysosomal morphology and distribution (PubMed:14668488). Binds to RAB10 following LRRK2-mediated RAB10 phosphorylation which leads to inhibition of ciliogenesis (PubMed:30398148). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GAPDH competitor of SIAH protein enhances life; GAPDH's competitor of SIAH1 protein enhances life; GOSPEL; Rab interacting lysosomal protein-like 1; Rab-interacting lysosomal-like protein 1; RILP-like protein 1
Gene Aliases: GOSPEL; RGD1307973; RILPL1; RLP1
UniProt ID: (Human) Q5EBL4, (Rat) D3ZUQ0
Entrez Gene ID: (Human) 353116, (Rat) 304469
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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