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Product Details
PA5-60614
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RIMBP2. Recombinant protein control fragment (Product #RP-97658).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646564
Product Specific Information
Immunogen sequence: RVDNITQISA QLSWLPTNSN YSHVIFLNEE EFDIVKAARY KYQFFNLRPN MAYKVKVLAK PHQMPWQLPL EQREKKEAFV EFSTLP
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 95%.
Target Information
The presynaptic active zone mediates synaptic vesicle exocytosis at a synapse. RIM proteins are active zone scaffolding molecules that--among others--mediate vesicle priming and directly or indirectly interact with most other essential presynaptic proteins. RIMBP2 encodes RIMS-binding protein 2 belonging to RIMBP family. RIMBP2 is supposed to be localized at cell membrane especially synaptic plasma membrane. By interacting with RIMS1, RIMS2, CACNA1D and CACNA1B via the SH3 domains, RIMBP2 mediates synaptic transmission as bifunctional linker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: protein phosphatase 1, regulatory subunit 133; RIM binding protein 2; RIM-BP2; RIMS-binding protein 2
Gene Aliases: KIAA0318; PPP1R133; RBP2; RIM-BP2; RIMBP2
UniProt ID: (Human) O15034
Entrez Gene ID: (Human) 23504
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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