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Immunogen sequence: SLGFRYCAILN AVNYISTVLA DWADNVFFLQ LQQAALEVFA ENNTLSKLQL GQLASMESSV FDDMINLLER LKHDMLTRQV DHVFREVKDA AKLYKKERWL SLPSQSEQAV MSLSSSACPL LLTLR
Highest antigen sequence identity to the following orthologs - mouse 96%, rat 97%.
Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER. May play a role in cell cycle checkpoint control. Essential for telomere length control.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HsRINT-1; RAD50 interactor 1; RAD50-interacting protein 1
Gene Aliases: RINT-1; RINT1
UniProt ID: (Human) Q6NUQ1
Entrez Gene ID: (Human) 60561
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