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Search Thermo Fisher Scientific
Proteintech
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Immunogen sequence: DRDKYVSGE FRFRHGYCKG NPRKMVKTWA EKEMRNLIRL NTAEIPCPEP IMLRSHVLVM SFIGKDDMPA PLLKNVQLSE SKARELYLQV IQYMRRMYQD ARLVHADLSE FNMLYHGGGV YIIDVSQSVE HDHPHALEFL RKDCANVNDF FMRHSVAVMT VRELFEFVTD PSITHENMDA YLSKAMEIAS QRTKEERSSQ DHVDEEVFKR AYIPRTLNEV KNYERDMDII MKLKEEDMAM NAQQDNILYQ TVTGLKKDLS GVQKVPALLE NQVEERTCSD SEDIGSSECS DTDSEEQGDH ARPKKHTTDP DIDKKERKKM VKEAQREKRK NKIPKHVKKR KEKTAKTKKG K (219-568 aa encoded by BC006104)
FXR1 is an RNA binding protein that interacts with the functionally-similar proteins FMR1 and FXR2. It may regulate intracellular transport and local transltion of certain mRNAs. These proteins shuttle between the nucleus and cytoplasm and associate with polyribosomes, predominantly with the 60S ribosomal subunit. FXR1 is required for embryonic and postnatal development of muscle tissue. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: RIO kinase 1; Serine/threonine-protein kinase RIO1
Gene Aliases: 3110046C13Rik; 5430416A05Rik; AD034; bA288G3.1; RIO1; RIOK1; RRP10
UniProt ID: (Human) Q9BRS2, (Mouse) Q922Q2
Entrez Gene ID: (Human) 83732, (Mouse) 71340, (Rat) 291061
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