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OriGene
RIT2 Monoclonal Antibody (OTI4A6), TrueMAB™
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Product Details
CF501701
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Mouse
/ IgG2a
Class
Monoclonal
Type
Antibody
Clone
OTI4A6
Immunogen
Full length human recombinant protein of human RIT2 produced in HEK293T cell.
Conjugate
Form
Lyophilized
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 8% trehalose
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
Target Information
Binds and exchanges GTP and GDP. Binds and modulates the activation of POU4F1 as gene expression regulator.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTP-binding protein Rit2; GTP-binding protein Roc2; RAS-like protein expressed in neuron; Ras-like protein expressed in neurons; Ras-like without CAAX 2; Ras-like without CAAX protein 2; Ric-like, expressed in neurons
Gene Aliases: RIBA; RIN; RIT2; ROC2
UniProt ID: (Human) Q99578, (Mouse) P70425
Entrez Gene ID: (Human) 6014, (Mouse) 19762
MAPK cascade
small GTPase mediated signal transduction
Ras protein signal transduction
chemical synaptic transmission
positive regulation of neuron projection development
regulation of endocytosis
regulation of Cdc42 protein signal transduction
maintenance of protein location in cell
intracellular signal transduction
positive regulation of MAPK cascade
regulation of calcium-mediated signaling
signal transduction
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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