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Invitrogen
RMI2 Polyclonal Antibody
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FIGURE: 1 / 9
RMI2 Antibody (PA5-95632) in IHC (P)
Immunohistochemical analysis of RMI2 in paraffin-embedded section of mouse liver tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-RMI2 antibody (Product # PA5-95632) overnight at 4°C. Biotinylated goat anti-rabbit IgG was use... View More
Product Details
PA5-95632
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence of human RMI2 (KMTDLSDNPIHESMWELEVEDLHRNIP).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 4mg trehalose
Contains
0.05mg sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2807434
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human T-47D whole cell, human HepG2 whole cell, human K562 whole cell, rat thymus tissue, mouse HEPA1-6 whole cell. IHC: human intestinal cancer tissue, human intestinal cancer tissue, rat liver tissue, human mammary cancer tissue, human mammary cancer tissue, mouse liver tissue. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
RMI2 is a protein coding gene, essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BLAP18; BLM-associated protein of 18 kDa; hRMI2; RecQ mediated genome instability 2; RecQ-mediated genome instability protein 2; RMI2, RecQ mediated genome instability 2, homolog
Gene Aliases: A630055G03Rik; BLAP18; C16orf75; Gm537; Gm929; RGD1563163; RMI2
UniProt ID: (Human) Q96E14, (Mouse) Q3UPE3
Entrez Gene ID: (Human) 116028, (Rat) 497856, (Mouse) 223970
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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