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Proteintech
RND2 Polyclonal Antibody
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Product Details
13844-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RND2 Fusion Protein Ag4807 (59-227 aa encoded by BC018096)
Conjugate
Form
Liquid
Concentration
0.27 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MWDTSGSSY YDNVRPLAYP DSDAVLICFD ISRPETLDSV LKKWQGETQE FCPNAKVVLV GCKLDMRTDL ATLRELSKQR LIPVTHEQGT VLAKQVGAVS YVECSSRSSE RSVRDVFHVA TVASLGRGHR QLRRTDSRRG MQRSAQLSGR PDRGNEGEIH KDRAKSCNLM (59-227 aa encoded by BC018096)
Target Information
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: aplysia ras-related homolog N (RhoN); CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; ras homolog N (RhoN); Rho family GTPase 2; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; rho7; Rnd2
Gene Aliases: ARHN; RHO7; RhoN; RND2; Rohn
UniProt ID: (Human) P52198, (Mouse) Q9QYM5
Entrez Gene ID: (Human) 8153, (Mouse) 11858
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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