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Abnova
RND2 Monoclonal Antibody (2D12)
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Product Details
H00008153-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Class
Monoclonal
Type
Antibody
Clone
2D12
Immunogen
RND2 (AAH18096, 1 a.a. approximately 169 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: MWDTSGSSYY DNVRPLAYPD SDAVLICFDI SRPETLDSVL KKWQGETQEF CPNAKVVLVG CKLDMRTDLA TLRELSKQRL IPVTHEQGTV LAKQVGAVSY VECSSRSSER SVRDVFHVAT VASLGRGHRQ LRRTDSRRGM QRSAQLSGRP DRGNEGEIHK DRAKSCNLM
Target Information
The Ras p21 family of guanine nucleotide proteins has been widely studied in view of its apparent role in signal transduction pathways and high frequency of mutations in human malignancies. It is now clear, however, that the Ras proteins (H-, K- and N-Ras p21) are members of a much larger superfamily of related proteins. Six members of this family, Rap 1A, Rap 1B, Rap 2, R-Ras, Ral A and Ral B, exhibit approximately 50% amino acid homology to Ras. The six mammalian Rho proteins (Rho A, B, C, G, 7 and 8) are approximately 30% homologous to Ras and are expressed in a wide range of cell types. Both Ras p21 and Rho p21, as well as other members of the Ras superfamily, contain a carboxy-terminal CAAX sequence (C, cysteine; A, aliphatic amino acid; X, any amino acid) which in the case of Ras has been shown to be essential for correct localization and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTD-3199J23.4; GTP-binding protein Rho7; ras homolog gene family, member N; Rho family GTPase 2; Rho-related GTP-binding protein Rho7; Rho-related GTP-binding protein RhoN; Rnd2
Gene Aliases: ARHN; RHO7; RhoN; RND2
UniProt ID: (Human) P52198
Entrez Gene ID: (Human) 8153
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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