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Product Details
PA5-64254
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RNF123. Recombinant protein control fragment (Product #RP-104052).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646620
Product Specific Information
Immunogen sequence: GNMPMLCPPE YMVCFLHRLI SALRYYWDEY KASNPHASFS EEAYIPPQVF YNGKVDYFDL QRLGGLLSHL RKTLKDDLAS KANIVIDPL
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 92%.
Target Information
Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF123; Kip1 ubiquitination-promoting complex protein 1; RING finger protein 123
Gene Aliases: FP1477; KPC1; RNF123
UniProt ID: (Human) Q5XPI4
Entrez Gene ID: (Human) 63891
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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