Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
25061-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF135 Fusion Protein Ag18821 (1-210 aa encoded by BC005084)
Conjugate
Form
Liquid
Concentration
0.45 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAGLGLGSA VPVWLAEDDL GCIICQGLLD WPATLPCGHS FCRHCLEALW GARDARRWAC PTCRQGAAQQ PHLRKNTLLQ DLADKYRRAA REIQAGSDPA HCPCPGSSSL SSAAARPRRR PELQRVAVEK SITEVAQELT ELVEHLVDIV RSLQNQRPLS ESGPDNELSI LGKENSWKPR LPPHAHCLTR ATLHSGELLG LLSGPSIQPL T (1-210 aa encoded by BC005084)
Target Information
The protein encoded by RNF135 contains a RING finger domain, a motif present in a variety of functionally distinct proteins and known to be involved in protein-protein and protein-DNA interactions. This gene is located in a chromosomal region known to be frequently deleted in patients with neurofibromatosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF135; MGC13061; REUL; RIG-I E3 ubiquitin ligase; RING finger protein 135; RING finger protein leading to RIG-I activation; RING-type E3 ubiquitin transferase RNF135; Riplet; U 2-3-0
Gene Aliases: 0610037N03Rik; 2410006N06Rik; L13; MMFD; REUL; Riplet; RNF135
UniProt ID: (Human) Q8IUD6, (Mouse) Q9CWS1
Entrez Gene ID: (Human) 84282, (Mouse) 71956
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
ribonucleoprotein complex binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support