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Product Details
PA5-110306
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 221-400 of human RNF149 (NP_775918.2).
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2855717
Product Specific Information
Immunogen sequence: FYYIQRFLYT GSQIGSQSHR KETKKVIGQL LLHTVKHGEK GIDVDAENCA VCIENFKVKD IIRILPCKHI FHRICIDPWL LDHRTCPMCK LDVIKALGYW GEPGDVQEMP APESPPGRDP AANLSLALPD DDGSDDSSPP SASPAESEPQ CDPSFKGDAG ENTALLEAGR SDSRHGGPIS
Target Information
RNF149 is a E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DNA polymerase-transactivated protein 2; E3 ubiquitin-protein ligase RNF149; Goliath-related E3 ubiquitin-protein ligase 4; RING finger protein 149; RING-type E3 ubiquitin transferase RNF149
Gene Aliases: 1600023E10Rik; AV037261; C76763; DNAPTP2; Gm15832; Greul4; OTTMUSG00000026591; RNF149
UniProt ID: (Human) Q8NC42, (Mouse) Q3U2C5
Entrez Gene ID: (Human) 284996, (Mouse) 67702
zinc ion binding
ligase activity
ubiquitin protein ligase activity
protein binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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