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Immunogen sequence: LLLHTVKHGE KGIDVDAENC AVCIENFKVK DIIRILPCKH IFHRICIDPW LLDHRTCPMC KLDVIKALGY WGEPGDVQEM PAPESPPGRD PAANLSLALP DDDGSDESSP PSASPAESEP QCDPSFKGDA GENT
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 72%.
RNF149 is a E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation.
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Protein Aliases: DNA polymerase-transactivated protein 2; E3 ubiquitin-protein ligase RNF149; RING finger protein 149; RING-type E3 ubiquitin transferase RNF149
Gene Aliases: DNAPTP2; RNF149
UniProt ID: (Human) Q8NC42
Entrez Gene ID: (Human) 284996
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