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RNF166 Antibody (PA5-76363) in IHC (P)
Immunohistochemistry analysis of RNF166 in paraffin-embedded mouse brain. Samples were incubated with RNF166 polyclonal antibody (Product # PA5-76363). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
Product Details
PA5-76363
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide of human RNF166.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2720090
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Target Information
RNF166 (RING finger protein 166) is a 237 amino acid protein that contains one RING-type zinc finger and a UIM (ubiquitin-interacting motif) repeat. Existing as two alternatively spliced isoforms, RNF166 is encoded by a gene that maps to human chromosome 16q24.3. Chromosome 16 encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF166; RING finger protein 166; RING-type E3 ubiquitin transferase RNF166; zinc finger protein 313; zinc finger protein 228
Gene Aliases: 1110031E24Rik; AW555115; RNF166; Zfp313l
UniProt ID: (Human) Q96A37, (Mouse) Q3U9F6, (Rat) Q6J1I7
Entrez Gene ID: (Human) 115992, (Mouse) 68718, (Rat) 365022
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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