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Product Details
20408-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF181 Fusion Protein Ag14233 (1-153 aa encoded by BC002803)
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MASYFDEHD CEPSDPEQET RTNMLLELAR SLFNRMDFED LGLVVDWDHH LPPPAAKTVV ENLPRTVIRG SQAELKCPVC LLEFEEEETA IEMPCHHLFH SSCILPWLSK TNSCPLCRYE LPTDDDTYEE HRRDKARKQQ QQHRLENLHG AMYT (1-153 aa encoded by BC002803)
Target Information
RNF181 binds the integrin alpha-IIb (ITGA2B)/beta-3 (ITGB3) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: E3 ubiquitin-protein ligase RNF181; RING finger protein 181
Gene Aliases: 1700047F16Rik; 2500002L14Rik; 6230415N01Rik; C77350; HSPC238; RNF181
UniProt ID: (Human) Q9P0P0, (Rat) Q6AXU4, (Mouse) Q9CY62
Entrez Gene ID: (Human) 51255, (Rat) 297337, (Mouse) 66510
ubiquitin-protein transferase activity
zinc ion binding
ligase activity
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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