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Invitrogen
RNF19A Polyclonal Antibody
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Product Details
PA5-54861
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RNF19A. Recombinant protein control fragment (Product #RP-93729).
Conjugate
Form
Liquid
Concentration
0.20 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646654
Product Specific Information
Immunogen sequence: EMCTDKNSIF STNTSSDNGL TSISKQIGDF IECPLCLLRH SKDRFPDIMT CHHRSCVDCL
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 93%.
Target Information
This gene encodes a member of the ring between ring fingers (RBR) protein family, and the encoded protein contains two RING-finger motifs and an in between RING fingers motif. This protein is an E3 ubiquitin ligase that is localized to Lewy bodies, and ubiquitylates synphilin-1, which is an interacting protein of alpha synuclein in neurons. The encoded protein may be involved in amyotrophic lateral sclerosis and Parkinson's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Dorfin; Double ring-finger protein; E3 ubiquitin-protein ligase RNF19A; p38; protein p38 interacting with transcription factor Sp1; ring finger protein 19; RING finger protein 19A; ring finger protein 19A, E3 ubiquitin protein ligase; ring-IBR-ring domain containing protein Dorfin
Gene Aliases: RNF19; RNF19A
UniProt ID: (Human) Q9NV58
Entrez Gene ID: (Human) 25897
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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