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          • Primary Antibodies ›
          • RNF213 Antibodies

          Bethyl Laboratories

          RNF213 Polyclonal Antibody

          View all (12) RNF213 antibodies
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          Datasheet
          Protocols
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          Cite RNF213 Polyclonal Antibody

          Product Details

          A305-841A

          Applications
          Tested Dilution
          Publications

          Immunoprecipitation (IP)

          15-20 µL/mg of lysate
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A region between residue 325 and 375 of human Protein ALO17.
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          phosphate, tris citrate

          Contains

          0.09% sodium azide

          Storage conditions

          4°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Target Information

          RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: ALK lymphoma oligomerization partner on chromosome 17; E3 ubiquitin-lipopolysaccharide ligase RNF213; E3 ubiquitin-protein ligase RNF213; Mysterin; RING finger protein 213

          View more View less

          Gene Aliases: ALO17; C17orf27; KIAA1554; KIAA1618; MYMY2; MYSTR; NET57; RNF213

          View more View less

          UniProt ID: (Human) Q63HN8

          View more View less

          Entrez Gene ID: (Human) 57674

          View more View less

          Function(s)
          ubiquitin-protein transferase activity zinc ion binding ligase activity ATPase activity
          Process(es)
          protein polyubiquitination angiogenesis sprouting angiogenesis ubiquitin-dependent protein catabolic process protein ubiquitination protein homooligomerization protein autoubiquitination negative regulation of non-canonical Wnt signaling pathway
          It has to be done as per old AB suggested Products section.
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