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Proteintech
RNF40 Polyclonal Antibody
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Product Details
15621-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RNF40 Fusion Protein Ag8047 (700-1001 aa encoded by BC006133)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VDELRSRIR ELEERDRRES KKIADEDALR RIRQAEEQIE HLQRKLGATK QEEEALLSEM DVTGQAFEDM QEQNGRLLQQ LREKDDANFK LMSERIKANQ IHKLLREEKD ELGEQVLGLK SQVDAQLLTV QKLEEKERAL QGSLGGVEKE LTLRSQALEL NKRKAVEAAQ LAEDLKVQLE HVQTRLREIQ PCLAESRAAR EKESFNLKRA QEDISRLRRK LEKQRKVEVY ADADEILQEE IKEYKARLTC PCCNTRKKDA VLTKCFHVFC FECVRGRYEA RQRKCPKCNA AFGAHDFHRI YIS (700-1001 aa encoded by B C006133)
Target Information
The protein encoded by this gene contains a RING finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein was reported to interact with the tumor suppressor protein RB1. Studies of the rat counterpart suggested that this protein may function as an E3 ubiquitin-protein ligase, and facilitate the ubiquitination and degradation of syntaxin 1, which is an essential component of the neurotransmitter release machinery.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 95 kDa retinoblastoma protein binding protein; 95 kDa retinoblastoma-associated protein; BRE1 E3 ubiquitin ligase homolog B; BRE1-B; DKFZp686K191; E3 ubiquitin-protein ligase BRE1B; MGC13051; Protein staring; Rb-associated protein; RBP95; RING finger protein 40; ring finger protein 40, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1B; staring protein; Syntaxin-1-interacting RING finger protein
Gene Aliases: AI848422; BRE1B; KIAA0661; mKIAA0661; RBP95; RNF40; STARING
UniProt ID: (Human) O75150, (Rat) Q8CJB9, (Mouse) Q3U319
Entrez Gene ID: (Human) 9810, (Rat) 266712, (Mouse) 233900
mRNA 3'-UTR binding
ubiquitin-protein transferase activity
protein binding
zinc ion binding
ligase activity
syntaxin-1 binding
ubiquitin conjugating enzyme binding
ubiquitin protein ligase binding
protein complex binding
protein homodimerization activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-dependent protein catabolic process
regulation of mitotic cell cycle
histone monoubiquitination
histone H2B ubiquitination
response to peptide hormone
negative regulation of mRNA polyadenylation
positive regulation of proteasomal protein catabolic process
positive regulation of protein polyubiquitination
positive regulation of histone H2B ubiquitination
chromatin modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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