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Product Details
PA5-110314
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 6-121 of human RPA3 (NP_002938.1).
Conjugate
Form
Liquid
Concentration
1.67 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2855725
Product Specific Information
Immunogen sequence: DLPRSRINAG MLAQFIDKPV CFVGRLEKIH PTGKMFILSD GEGKNGTIEL MEPLDEEISG IVEVVGRVTA KATILCTSYV QFKEDSHPFD LGLYNEAVKI IHDFPQFYPL GIVQHD
Target Information
Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Replication factor A protein 3; Replication protein A 14 kDa subunit; replication protein A3, 14kDa; RF-A protein 3; RP-A p14
Gene Aliases: 14kDa; C330026P08Rik; REPA3; RP-A p14; RPA14; RPA3
UniProt ID: (Human) P35244, (Mouse) Q9CQ71
Entrez Gene ID: (Human) 6119, (Mouse) 68240, (Rat) 296883
double-strand break repair via homologous recombination
DNA replication
DNA repair
base-excision repair
nucleotide-excision repair
mismatch repair
DNA recombination
cellular response to DNA damage stimulus
regulation of mitotic cell cycle
regulation of cell proliferation
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
transcription-coupled nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
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If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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