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Bethyl Laboratories
RPA70 Polyclonal Antibody
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RPA70 Antibody (A300-241A) in IHC (P)
Detection of human RPA70 by immunohistochemistry. Samples: FFPE serial sections of human ovarian carcinoma. Antibodies: Affinity purified rabbit anti-RPA70 (Product # A300-241A) (Lot 2) used at a dilution of 1:1,000 (1 µg/mL) (left) and A300-241A (Lot 3) used at a dilution of 1:5,000 (0.2 µg/mL) (right). Detection: DAB.
Product Details
A300-241A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Region between residues 350 and 400 of Human replication protein A1, 70kDa.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
phosphate/tris citrate, pH 7-8
Contains
0.09% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Application Note: For IHC, epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
Based on 100% sequence identity, this antibody is predicted to react with Orangutan
Target Information
This gene Plays an essential role in several cellular processes in DNA metabolism including replication, recombination and DNA repair. Binds and subsequently stabilizes single-stranded DNA intermediates and thus prevents complementary DNA from reannealing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: MSTP075; Replication factor A protein 1; Replication protein A 70 kDa DNA-binding subunit; replication protein A1, 70kDa; RF-A protein 1; RP-A p70; Single-stranded DNA-binding protein
Gene Aliases: 5031405K23Rik; 70kDa; AA589576; AW557552; HSSB; MST075; REPA1; RF-A; RP-A; Rpa; RPA1; RPA70
UniProt ID: (Human) P27694, (Mouse) Q8VEE4
Entrez Gene ID: (Human) 6117, (Mouse) 68275
G1/S transition of mitotic cell cycle
telomere maintenance via recombination
telomere maintenance
double-strand break repair via homologous recombination
DNA replication
DNA-dependent DNA replication
DNA repair
transcription-coupled nucleotide-excision repair
base-excision repair
nucleotide-excision repair
nucleotide-excision repair, preincision complex stabilization
nucleotide-excision repair, preincision complex assembly
nucleotide-excision repair, DNA incision, 3'-to lesion
nucleotide-excision repair, DNA incision, 5'-to lesion
nucleotide-excision repair, DNA gap filling
mismatch repair
DNA recombination
protein sumoylation
translesion synthesis
nucleotide-excision repair, DNA incision
interstrand cross-link repair
error-prone translesion synthesis
DNA damage response, detection of DNA damage
error-free translesion synthesis
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
cell cycle checkpoint
in utero embryonic development
cellular response to DNA damage stimulus
meiotic nuclear division
positive regulation of cell proliferation
hemopoiesis
homeostasis of number of cells within a tissue
chromosome organization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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