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Invitrogen
RPGR Polyclonal Antibody
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Product Details
PA5-51607
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RPGR. Recombinant protein control fragment (Product #RP-92146).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646715
Product Specific Information
Immunogen sequence: EINDTCLSVA TFLPYSSLTS GNVLQRTLSA RMRRRERERS PDSFSMRRTL PPIEGTLGLS ACFLPNSVFP RCSERNLQES VLSEQDLMQP EEPDYLLDEM TKEAEIDNSS TVESLGETTD ILNMTHIMSL N
Highest antigen sequence identity to the following orthologs: Mouse - 46%, Rat - 41%.
Target Information
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: retinitis pigmentosa 15; retinitis pigmentosa 3 GTPase regulator; X-linked retinitis pigmentosa GTPase regulator
Gene Aliases: COD1; CORDX1; CRD; orf15; PCDX; RP15; RP3; RPGR; XLRP3
UniProt ID: (Human) Q92834
Entrez Gene ID: (Human) 6103
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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