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Invitrogen
RPGRIP1L Polyclonal Antibody
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Product Details
PA5-58777
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RPGRIP1L. Recombinant protein control fragment (Product #RP-98219).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2646717
Product Specific Information
Immunogen sequence: KNTITLEVHQ AYSTEYETIA ACQLKFHEIL EKSGRIFCTA SLIGTKGDIP NFGTVEYWFR LRVPMDQAIR LYRERAKALG YITSNFKGPE HMQSLSQQAP KTAQLSSTDS TDGNL
Highest antigen sequence identity to the following orthologs: Mouse - 85%, Rat - 87%.
Target Information
The protein encoded by this gene can localize to the basal body-centrosome complex or to primary cilia and centrosomes in ciliated cells. The encoded protein has been found to interact with nephrocystin-4. Defects in this gene are a cause of Joubert syndrome type 7 and Meckel syndrome type 5. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp686C0668; fantom homolog; Nephrocystin-8; Protein fantom; protein phosphatase 1, regulatory subunit 134; RPGR-interacting protein 1-like protein; RPGRIP1-like; RPGRIP1-like protein
Gene Aliases: CORS3; FTM; JBTS7; KIAA1005; MKS5; NPHP8; PPP1R134; RPGRIP1L
UniProt ID: (Human) Q68CZ1
Entrez Gene ID: (Human) 23322
in utero embryonic development
establishment of planar polarity
kidney development
liver development
establishment or maintenance of cell polarity
determination of left/right symmetry
regulation of smoothened signaling pathway
neural tube patterning
cerebellum development
lateral ventricle development
olfactory bulb development
corpus callosum development
embryonic forelimb morphogenesis
embryonic hindlimb morphogenesis
cilium assembly
camera-type eye development
nose development
negative regulation of G-protein coupled receptor protein signaling pathway
pericardium development
cochlea development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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