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Bioss
RPL11 Polyclonal Antibody
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FIGURE: 1 / 2
RPL11 Antibody (BS-5715R) in IHC (P)
Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with RPL11 Polyclonal Antibody, Unconjugated (bs-5715R) at 1:200 overnight at 4°C, DAB staining.
Product Details
BS-5715R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human RPL11, amino acids 101-178.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L11; cell growth-inhibiting protein 34; CLL-associated antigen KW-12; Large ribosomal subunit protein uL5; RP11-223J15.3
Gene Aliases: 2010203J19Rik; DBA7; GIG34; L11; RPL11
UniProt ID: (Human) P62913, (Mouse) Q9CXW4, (Rat) P62914
Entrez Gene ID: (Human) 6135, (Mouse) 67025, (Rat) 362631
rRNA processing
translation
protein targeting
protein localization to nucleus
ribosomal large subunit biogenesis
ribosomal large subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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