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Invitrogen
RPL11 Polyclonal Antibody
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RPL11 Antibody (PA5-27468) in IHC (P)
RPL11 Polyclonal Antibody detects RPL11 protein at cytosol and nucleus on HeLa xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HeLa xenograft. RPL11 Polyclonal Antibody (Product # PA5-27468) dilution: 1:500. Antigen Retrieval: EDTA based buffer, pH 8.0, 15 min.
Product Details
PA5-27468
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RPL11. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2544944
Product Specific Information
Recommended positive controls: HeLa, mouse Liver.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (98%), Drosophila (85%), Xenopus laevis (96%), Dog (100%), Pig (99%), Chicken (98%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 60S ribosomal protein L11; cell growth-inhibiting protein 34; CLL-associated antigen KW-12; Large ribosomal subunit protein uL5; RP11-223J15.3
Gene Aliases: 2010203J19Rik; DBA7; GIG34; L11; RPL11
UniProt ID: (Human) P62913, (Mouse) Q9CXW4
Entrez Gene ID: (Human) 6135, (Mouse) 67025
rRNA processing
translation
protein targeting
protein localization to nucleus
ribosomal large subunit biogenesis
ribosomal large subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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