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          • Primary Antibodies ›
          • RPL22/RPL22L1 Antibodies

          Invitrogen

          RPL22/RPL22L1 Polyclonal Antibody

          2 References
          View all (2) RPL22/RPL22L1 antibodies
          Datasheet
          Protocols
          Questions & Answers
          Datasheet
          Protocols
          Questions & Answers

          Cite RPL22/RPL22L1 Polyclonal Antibody

          Product Details

          PA5-68320

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000-1:3,000
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Published species

          Mouse

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Synthesized peptide derived from human RPL22/RPL22L1.

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          1 mg/mL

          Purification

          affinity chromatography

          Storage buffer

          PBS, pH 7.4, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2692054

          Product Specific Information

          Predicted to react with Mouse and Rat samples.

          Target Information

          Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2. [provided by RefSeq, Jul 2008].

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: 60S ribosomal protein L22; 60S ribosomal protein L22-like 1; EAP; EBER-associated protein; Epstein-Barr virus small RNA-associated protein; Epstein-Barr-encoded RNA-associated protein; heparin-binding protein 15; Heparin-binding protein HBp15; Large ribosomal subunit protein eL22; Large ribosomal subunit protein eL22-like 1; Ribosomal protein eL22-like; Ribosomal protein eL22-like 1; ribosomal protein L22-like 1

          View more View less

          Gene Aliases: 2700038K18Rik; 3110001N18Rik; AU041196; EAP; HBP15; HBP15/L22; L22; RGD1309517; RPL22; RPL22L1

          View more View less

          UniProt ID: (Human) P35268, (Human) Q6P5R6, (Rat) P47198, (Mouse) P67984, (Mouse) Q9D7S7

          View more View less

          Entrez Gene ID: (Human) 6146, (Human) 200916, (Rat) 81768, (Mouse) 19934, (Mouse) 68028, (Rat) 361923

          View more View less

          Function(s)
          RNA binding structural constituent of ribosome protein binding heparin binding poly(A) RNA binding molecular_function
          Process(es)
          translation alpha-beta T cell differentiation biological_process cytoplasmic translation nuclear-transcribed mRNA catabolic process, nonsense-mediated decay rRNA processing translational initiation SRP-dependent cotranslational protein targeting to membrane viral transcription
          It has to be done as per old AB suggested Products section.
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