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Invitrogen
RPL6 Polyclonal Antibody
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Product Details
PA5-30217
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human RPL6. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2547691
Product Specific Information
Recommended positive controls: A549, H1299, HCT116, MCF-7.
Predicted reactivity: Mouse (91%), Rat (91%), Xenopus laevis (81%), Pig (94%), Chicken (83%), Rhesus Monkey (99%), Chimpanzee (100%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L6E family of ribosomal proteins. It is located in the cytoplasm. The protein can bind specifically to domain C of the tax-responsive enhancer element of human T-cell leukemia virus type 1, and it has been suggested that the protein may participate in tax-mediated transactivation of transcription. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 60S ribosomal protein L6; DNA-binding protein TAXREB107; Large ribosomal subunit protein eL6; Neoplasm-related protein C140; TAX-responsive enhancer element-binding protein 107; TAXREB107
Gene Aliases: L6; RPL6; SHUJUN-2; TAXREB107; TXREB1
UniProt ID: (Human) Q02878, (Mouse) P47911, (Rat) P21533
Entrez Gene ID: (Human) 6128, (Mouse) 19988, (Rat) 117042
translation
ribosomal large subunit assembly
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
cytoplasmic translation
regulation of transcription, DNA-templated
rRNA processing
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
cell-cell adhesion
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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