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Product Details
H00006218-M01A
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
2C7
Immunogen
RPS17 (NP_001012, 36 a.a. approximately 135 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
See Label
Storage buffer
ascites
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Sequence of this protein is as follows: EEIAIIPSKK LRNKIAGYVT HLMKRIQRGP VRGISIKLQE EERERRDNYV PEVSALDQEI IEVDPDTKEM LKLLDFGSLS NLQVTQPTVG MNFKTPRGPV
Target Information
Ribosomes, the organelles that catalyze protein synthesis, are composed of a small subunit (40S) and a large subunit (60S) that consist of over 80 distinct ribosomal proteins. Mammalian ribosomal proteins are encoded by multigene families that contain processed pseudogenes and one functional intron-containing gene within their coding regions. Ribosomal Protein S17, also known as RPS17, RPS17L1 or RPS17L2, is a 135 amino acid protein that is a component of the 40S subunit. Localized to the cytoplasm and expressed ubiquitously, Ribosomal Protein S17 belongs to the S17e family of ribosomal proteins and functions in protein synthesis. Mutations in the gene encoding Ribosomal Protein S17 are associated with Diamond-Blackfan anemia (DBA), a rare congenital disorder characterized by defective differentiation of pro-erythroblasts. Like most ribosomal proteins, Ribosomal Protein S17 exists as multiple processed pseudogenes that are scattered throughout the genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40S ribosomal protein S17; Small ribosomal subunit protein eS17
Gene Aliases: DBA4; RPS17; RPS17L; RPS17L1; RPS17L2; S17
UniProt ID: (Human) P08708, (Mouse) P63276, (Rat) P04644
Entrez Gene ID: (Human) 6218, (Mouse) 20068, (Rat) 29286
ribosomal small subunit assembly
rRNA processing
translation
erythrocyte homeostasis
ribosomal small subunit biogenesis
translational elongation
biological_process
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
translational initiation
SRP-dependent cotranslational protein targeting to membrane
viral transcription
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