Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-106716
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RRAGB(Accession Q5VZM2), corresponding to amino acid residues R79-T129.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2854384
Product Specific Information
Antibody detects endogenous levels of total RRAGB.
Target Information
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: GTP-binding protein ragB; Rag B; ragB; Ras-related GTP binding B; Ras-related GTP-binding protein B; RRAGB; rragB {ECO:0000312|RGD:619805}
Gene Aliases: bA465E19.1; RAGB; RRAGB
UniProt ID: (Human) Q5VZM2, (Rat) Q63487, (Mouse) Q6NTA4
Entrez Gene ID: (Human) 10325, (Rat) 117043, (Mouse) 245670
cell cycle arrest
regulation of autophagy
macroautophagy
regulation of TOR signaling
positive regulation of TOR signaling
cellular response to amino acid starvation
cellular protein localization
cellular response to amino acid stimulus
biological_process
metabolic process
cellular response to starvation
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support