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Abnova
RRAGB Monoclonal Antibody (2B8)
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Product Details
H00010325-M01
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2a, kappa
Class
Monoclonal
Type
Antibody
Clone
2B8
Immunogen
RRAGB (AAH34726, 1 a.a. approximately 346 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Form
Liquid
Concentration
0.32 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
Product Specific Information
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: MEESDSEKTT EKENLGPRMD PPLGEPEGSL GWVLPNTAMK KKVLLMGKSG SGKTSMRSII FANYIARDTR RLGATIDVEH SHVRFLGNLV LNLWDCGGQD TFMENYFTSQ RDNIFRNVEV LIYVFDVESR ELEKDMHYYQ SCLEAILQNS PDAKIFCLVH KMDLVQEDQR DLIFKEREED LRRLSRPLEC SCFRTSIWDE TLYKAWSSIV YQLIPNVQQL EMNLRNFAEI IEADEVLLFE RATFLVISHY QCKEQRDAHR FEKISNIIKQ FKLSCSKLAA SFQSMEVRNS NFAAFIDIFT SNTYVMVVMS DPSIPSAATL INIRNARKHF EKLERVDGPK QCLLMR
Target Information
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: GTP-binding protein ragB; Rag B; Ras-related GTP binding B; Ras-related GTP-binding protein B; RRAGB
Gene Aliases: bA465E19.1; RAGB; RRAGB
UniProt ID: (Human) Q5VZM2
Entrez Gene ID: (Human) 10325
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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