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Immunogen sequence: AQTMEALLAL LPELSVLAQQ NYTEWLQDLK EKGPTLLKHP PAPAEPSSDL ASKLREAEET QSTLQAECDQ YRSILAETEG MLRDLQKSVE EEEQVWRAKV GAAEEELQKS RVTVKHLEEI VEKLKGELES SDQVREHTLH LEAELEKHMA AASAECQNYA KEVAGLRQLL LESQSQLDAA KSEAQKQSDE LALVRQQLSE MKSHVEDGDI AGAPASSPEA PPAEQDPVQL KTQLEWTEAI LEDEQTQRQK LTAEFEEAQT SACRLQEELE KLRTAGPLES SETEEASQLK ERLEKEKKLT SDLGRAATRL QELLKTTQEQ LAREKDTVKK LQEQLEKAED GSSSKEGTSV
Analysis of cDNA clones indicates that ribosome binding protein 1 may exist in different forms due to removal of tandem repeats, or partial intraexonic splicing of RRBP1. The form presented here is lacking the canine p180 ribosome-binding domain, NQGKKAEGAQ, which is tandemly repeated close to the N-terminus in other forms that haven't been fully characterized. RRBP1 has been excluded as a candidate gene in the cause of Alagille syndrome. Alternate splicing results in multiple transcript variants.
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Protein Aliases: 180 kDa ribosome receptor homolog; ES/130-related protein; mRRp; ribosome binding protein 1 homolog 180kDa (dog); Ribosome receptor protein; Ribosome-binding protein 1; RP11-462D18.3; RRp
Gene Aliases: 1700087N07Rik; 5730465C04Rik; ES/130; ES130; hES; KIAA1398; mKIAA1398; mRRp0; mRRp1.8; mRRp10; mRRp15a; mRRp15b; mRRp16.8; mRRp2; mRRp41; mRRp47; mRRp5.4; p180; RRBP1; RRp
UniProt ID: (Human) Q9P2E9, (Mouse) Q99PL5
Entrez Gene ID: (Human) 6238, (Mouse) 81910
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