Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
PA5-99708
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human RREB1(Accession Q92766), corresponding to amino acid residues P878-Y928.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2818641
Product Specific Information
Antibody detects endogenous levels of total RREB1.
Target Information
The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: DNA-binding protein; Finger protein in nuclear bodies; hindsight homolog; Raf-responsive zinc finger protein LZ321; Ras-responsive element-binding protein 1; RREB 1; RREB-1; Zep 1; Zep-1; Zep1; zinc finger motif enhancer binding protein 1; Zinc finger motif enhancer-binding protein 1; zinc finger motif-enhancer binding-protein 1
Gene Aliases: FINB; HNT; LZ321; RREB-1; RREB1; Zep-1
UniProt ID: (Human) Q92766
Entrez Gene ID: (Human) 6239
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
Ras protein signal transduction
multicellular organism development
positive regulation of epithelial cell migration
positive regulation of mammary gland epithelial cell proliferation
positive regulation of transcription, DNA-templated
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of wound healing, spreading of epidermal cells
positive regulation of lamellipodium morphogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support