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Invitrogen
RRM1 Recombinant Rabbit Monoclonal Antibody (HL1230)
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Product Details
MA5-46963
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Dog,
Cat,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
HL1230
Immunogen
Recombinant protein encompassing a sequence within the center region of human RRM1. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2938035
Product Specific Information
Store as concentrated solution.
Centrifuge briefly prior to opening vial.
Target Information
RRM1 (Ribonucleotide reductase M1 polypeptide) is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme which catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RRM1 is involved in carcinogenesis, tumor progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: R RRM 1; RI RI RR 1; Ribonucleoside-diphosphate reductase large subunit; Ribonucleoside-diphosphate reductase subunit M1; Ribonucleotide reductase large subunit; ribonucleotide reductase M1 polypeptide; ribonucleotide reductase, R1 subunit; RIR 1
Gene Aliases: R1; RIR1; RnrM1; RR1; RRM1
UniProt ID: (Human) P23921, (Mouse) P07742
Entrez Gene ID: (Human) 6240, (Dog) 476823, (Rat) 685579, (Mouse) 20133
mitotic cell cycle
pyrimidine nucleobase metabolic process
DNA replication
male gonad development
deoxyribonucleotide biosynthetic process
response to ionizing radiation
nucleobase-containing small molecule interconversion
cell proliferation in forebrain
protein heterotetramerization
oxidation-reduction process
retina development in camera-type eye
protein oligomerization
metabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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