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Invitrogen
RSK4 Polyclonal Antibody
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FIGURE: 1 / 1
RSK4 Antibody (PA5-90097) in WB
Western blot analysis of RSK4 in mouse kidney. Samples were incubated with RSK4 Polyclonal antibody (Product # PA5-90097) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 10s.
Product Details
PA5-90097
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 646-745 of human RPS6KA6 (NP_0553111)
Conjugate
Form
Liquid
Concentration
1.47 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2805923
Product Specific Information
Immunogen sequence: GGNWDNISDG AKDLLSHMLH MDPHQRYTAE QILKHSWITH RDQLPNDQPK RNDVSHVVKG AMVATYSALT HKTFQPVLEP VAASSLAQRR SMKKRTSTGL; Positive Samples: Mouse kidney; Cellular Location: Cytoplasm, Nucleus, cytosol
Target Information
RPS6KA6 (RSK4) is a member of the RSK kinases family. RSK family members are activated by ERKs and mitogens and are unusual in that they contain 2 non-identical kinase domains. RSK4 encodes a member of ribosomal S6 kinase family, serine-threonine protein kinases which are regulated by growth factors. The encoded protein may be distinct from other members of this family, however, as studies suggest it is not growth factor dependent and may not participate in the same signaling pathways.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Ribosomal protein S6 kinase alpha-6; S6K-alpha-6; S6KA6
Gene Aliases: 2610524K04Rik; Rps6ka6; RSK4; S6K-alpha-6
UniProt ID: (Mouse) Q7TPS0
Entrez Gene ID: (Mouse) 67071
regulation of translation
protein phosphorylation
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
phosphorylation
intracellular signal transduction
negative regulation of embryonic development
negative regulation of ERK1 and ERK2 cascade
negative regulation of mesoderm development
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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