Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
RSPO1 Polyclonal Antibody
Promotion
View available promotion(s)
Promo code: {{promo.promoCode}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Product Details
PA5-121183
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 90-210 of human RSPO1 (NP_001033722.1).
Conjugate
Form
Liquid
Concentration
0.76 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal, 0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2914755
Product Specific Information
Positive test controls include: Mouse testis. The target is usually found in the following locations: Secreted.
Immunogen sequence: DMNKCIKCKI EHCEACFSHN FCTKCKEGLY LHKGRCYPAC PEGSSAANGT MECSSPAQCE MSEWSPWGPC SKKQQLCGFR RGSEERTRRV LHAPVGDHAA CSDTKETRRC TVRRVPCPEG Q
Target Information
This gene is a member of the R-spondin family and encodes a secreted activator protein with two cystein-rich, furin-like domains and one thrombospondin type 1 domain. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Cristin-3; Cysteine-rich and single thrombospondin domain-containing protein 3; FLJ40906; hRspo1; mCristin-3; R-spondin homolog; R-spondin-1; Roof plate-specific spondin-1; RP11-566C13.1; thrombospondin type 1 domain containing gene Rspondin
Gene Aliases: CRISTIN3; R-spondin; RGD1565558; RSPO; RSPO1; Rspondin
UniProt ID: (Human) Q2MKA7, (Mouse) Q3V1S3
Entrez Gene ID: (Human) 284654, (Rat) 313589, (Mouse) 192199
positive regulation of protein phosphorylation
regulation of receptor internalization
male meiosis
biological_process
regulation of gene expression
positive regulation of Wnt signaling pathway
canonical Wnt signaling pathway
positive regulation of canonical Wnt signaling pathway
positive regulation of non-canonical Wnt signaling pathway
regulation of male germ cell proliferation
Wnt signaling pathway
response to stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support