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Proteintech
RSPO3 Polyclonal Antibody
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Product Details
17193-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
RSPO3 Fusion Protein Ag9899 (27-272 aa encoded by BC022367)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: GRRQRRMHP NVSQGCQGGC ATCSDYNGCL SCKPRLFFAL ERIGMKQIGV CLSSCPSGYY GTRYPDINKC TKCKADCDTC FNKNFCTKCK SGFYLHLGKC LDNCPEGLEA NNHTMECVSI VHCEVSEWNP WSPCTKKGKT CGFKRGTETR VREIIQHPSA KGNLCPPTNE TRKCTVQRKK CQKGERGKKG RERKRKKPNK GESKEAIPDS KSLESSKEIP EQRENKQQQK KRKVQDKQKS VSVSTVH (27-272 aa encoded by BC022367)
Target Information
RSPO3 is a member of the R-spondin family and plays a role in the regulation of Wnt (wingless-type MMTV integration site family)/beta-catenin and Wnt/planar cell polarity (PCP) signaling pathways, which are involved in development, cell growth and disease pathogenesis. RSPO3 has been shown to be involved in regulating the balance between angioblast and blood cell specification during embryonic vasculogenesis and angiogenesis and may be involved in tumor development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Cabriolet; cristin 1; Cristin-1; Cysteine-rich and single thrombospondin domain-containing protein 1; hPWTSR; hRspo3; Nucleopondin; Protein with TSP type-1 repeat; R-spondin 3 homolog; R-spondin 3-like protein; R-spondin-3; Roof plate-specific spondin-3; Thrombospondin type-1 domain-containing protein 2; thrombospondin, type I, domain 2; thrombospondin, type I, domain containing 2
Gene Aliases: 2810459H04Rik; AW742308; CRISTIN1; PWTSR; RGD1563246; RSPO3; THSD2
UniProt ID: (Human) Q9BXY4, (Mouse) Q2TJ95
Entrez Gene ID: (Human) 84870, (Mouse) 72780, (Rat) 498997
angiogenesis
Wnt signaling pathway
response to stimulus
branching involved in labyrinthine layer morphogenesis
positive regulation of canonical Wnt signaling pathway
biological_process
canonical Wnt signaling pathway
blood vessel remodeling
sprouting angiogenesis
positive regulation of Wnt signaling pathway
positive regulation of non-canonical Wnt signaling pathway
positive regulation of Wnt signaling pathway, planar cell polarity pathway
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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