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Recommended positive controls: NT2D1, IMR32, U87-MG, MCF-7.
Predicted reactivity: Mouse (95%), Rat (97%), Chicken (87%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a protein that contains a RUN domain and a FYVE-type zinc finger domain. The encoded protein binds to phosphatidylinositol-3-phosphate (PI3P) and plays a role in early endosomal trafficking, tethering and fusion through interactions with small GTPases including Rab4, Rab5 and Rab14. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FYVE-finger protein EIP1; La-binding protein 1; Rab4-interacting protein; RUN and FYVE domain-containing protein 1; Zinc finger FYVE domain-containing protein 12
Gene Aliases: RABIP4; RUFY1; ZFYVE12
UniProt ID: (Human) Q96T51
Entrez Gene ID: (Human) 80230
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