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NeoBiotechnologies
RXRG/NR2B3 (Transcription Factor) Monoclonal Antibody (PCRP-RXRG-5H4)
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Product Details
6258-MSM3-P0
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG1
Class
Monoclonal
Type
Antibody
Clone
PCRP-RXRG-5H4
Immunogen
Recombinant full-length human RXRG protein
Conjugate
Form
Liquid
Concentration
200 µg/mL
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C, do not freeze
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Predicted to react in Mouse, Rat, Chick
Target Information
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Nuclear receptor subfamily 2 group B member 3; Retinoic acid receptor RXR-gamma; retinoid X receptor; Retinoid X receptor gamma; retinoid X receptor, gamma; RXR gamma
Gene Aliases: NR2B3; RXRC; RXRG
UniProt ID: (Human) P48443
Entrez Gene ID: (Human) 6258
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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