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Recommended positive controls: 293T, A431, H1299, HeLaS3.
Predicted reactivity: Mouse (97%), Rat (96%), Zebrafish (95%), Xenopus laevis (90%), Chicken (98%), Bovine (99%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The transport of protein and large RNAs through the nuclear pore complexes is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exp7; Exportin-7; RAN binding protein 16; Ran-binding protein 16
Gene Aliases: 4930506C02Rik; BB164534; EXP7; KIAA0745; mKIAA0745; RANBP16; XPO7
UniProt ID: (Human) Q9UIA9, (Mouse) Q9EPK7
Entrez Gene ID: (Human) 23039, (Mouse) 65246
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