Proteintech

RelB Polyclonal Antibody

RelB Antibody in Immunocytochemistry (ICC/IF)

FIGURE: 1 / 10

RelB Antibody (25027-1-AP) in ICC/IF

Immunofluorescent analysis of HeLa cells using 25027-1-AP (RELB antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IGG.

RelB Antibody in Immunohistochemistry (Paraffin) (IHC (P))

RelB Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

25027-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 4 publications 4 publications

Immunohistochemistry (IHC)

View 1 publication 1 publication

Immunohistochemistry (Paraffin) (IHC (P))

1:20-1:200

Immunocytochemistry (ICC/IF)

1:10-1:100

View 1 publication 1 publication

Flow Cytometry (Flow)

Assay-dependent

View 1 publication 1 publication

Immunoprecipitation (IP)

0.5-4.0 µg

Product Specifications

Species Reactivity

Human, Rat

Published species

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

RELB Fusion Protein Ag13824 (264-579 aa encoded by BC028013)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.21 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: NVVRICFQA SYRDQQGQMR RMDPVLSEPV YDKKSTNTSE LRICRINKES GPCTGGEELY LLCDKVQKED ISVVFSRASW EGRADFSQAD VHRQIAIVFK TPPYEDLEIV EPVTVNVFLQ RLTDGVCSEP LPFTYLPRDH DSYGVDKKRK RGMPDVLGEL NSSDPHGIES KRRKKKPAIL DHFLPNHGSG PFLPPSALLP DPDFFSGTVS LPGLEPPGGP DLLDDGFAYD PTAPTLFTML DLLPPAPPHA SAVVCSGGAG AVVGETPGPE PLTLDSYQAP GPGDGGTASL VGSNMFPNHY REAAFGGGLL SPGPEAT (264-579 aa encoded by BC028013 )

Target Information

The NFkB transcription factor was originally identified as a protein complex consisting of a DNA-binding subunit and an associated protein. The DNAbinding subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A second protein designated p52 (previously referred to as p49) has been identified that can act as an alternative NFkB subunit. Rel B does not bind with high affinity to NFkB sites, but heterodimers between Rel B and p50 bind with an affinity comparable to that of p50 NFkB homodimers. However, Rel B/p50 heterodimers, in contrast to NFkB heterodimers, transactivates transcription of promotors containing kB binding sites.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

p38-mediated FOXN3 phosphorylation modulates lung inflammation and injury through the NF-κB signaling pathway.

Nucleic acids research

Zhu X,Huang B,Zhao F,Lian J,He L,Zhang Y,Ji L,Zhang J,Yan X,Zeng T,Ma C,Liang Y,Zhang C,Lin J

Tue Mar 21 00:00:00 UTC 2023

NF-κB fingerprinting reveals heterogeneous NF-κB composition in diffuse large B-cell lymphoma.

Frontiers in oncology

Jayawant E,Pack A,Clark H,Kennedy E,Ghodke A,Jones J,Pepper C,Pepper A,Mitchell S

Tue Jun 20 00:00:00 UTC 2023

Human hematopoietic stem cell vulnerability to ferroptosis.

Cell

Zhao J,Jia Y,Mahmut D,Deik AA,Jeanfavre S,Clish CB,Sankaran VG

Thu Feb 16 00:00:00 UTC 2023

Circulating Myeloid-derived Suppressor Cells Facilitate Invasion of Thyroid Cancer Cells by Repressing miR-486-3p.

The Journal of clinical endocrinology and metabolism

Chen L,Xiong L,Hong S,Li J,Huo Z,Li Y,Chen S,Zhang Q,Zhao R,Gingold JA,Zhu X,Lv W,Li Y,Yu S,Xiao H

Sat Aug 01 00:00:00 UTC 2020

Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma.

Cell death & disease

Xiao X,Li H,Jin H,Jin J,Yu M,Ma C,Tong Y,Zhou L,Lei H,Xu H,Zhang W,Liu W,Wu Y

Thu Sep 14 00:00:00 UTC 2017

Identification of 11(13)-dehydroivaxillin as a potent therapeutic agent against non-Hodgkin's lymphoma.

Cell death & disease

Xiao X,Li H,Jin H,Jin J,Yu M,Ma C,Tong Y,Zhou L,Lei H,Xu H,Zhang W,Liu W,Wu Y

Thu Sep 14 00:00:00 UTC 2017

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma.

Nature genetics

Jiang L,Gu ZH,Yan ZX,Zhao X,Xie YY,Zhang ZG,Pan CM,Hu Y,Cai CP,Dong Y,Huang JY,Wang L,Shen Y,Meng G,Zhou JF,Hu JD,Wang JF,Liu YH,Yang LH,Zhang F,Wang JM,Wang Z,Peng ZG,Chen FY,Sun ZM,Ding H,Shi JM,Hou J,Yan JS,Shi JY,Xu L,Li Y,Lu J,Zheng Z,Xue W,Zhao WL,Chen Z,Chen SJ

Tue Sep 01 00:00:00 UTC 2015

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma.

Nature genetics

Tue Sep 01 00:00:00 UTC 2015

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma.

Nature genetics

Tue Sep 01 00:00:00 UTC 2015

Exome sequencing identifies somatic mutations of DDX3X in natural killer/T-cell lymphoma.

Nature genetics

Tue Sep 01 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: avian reticuloendotheliosis viral (v-rel) oncogene related B; I-Rel; OTTHUMP00000221313; rel b; Transcription factor RelB; v-rel avian reticuloendotheliosis viral oncogene homolog B; v-rel avian reticuloendotheliosis viral oncogene homolog B (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3); v-rel reticuloen; v-rel reticuloendotheliosis viral oncogene homolog B; v-rel reticuloendotheliosis viral oncogene homolog B, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

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Gene Aliases: I-REL; IREL; REL-B; RELB

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UniProt ID: (Human) Q01201

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Entrez Gene ID: (Human) 5971, (Rat) 100360982

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Function(s)

RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding core promoter binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription corepressor activity protein binding RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding DNA binding

Process(es)

negative regulation of transcription from RNA polymerase II promoter stimulatory C-type lectin receptor signaling pathway transcription, DNA-templated inflammatory response I-kappaB kinase/NF-kappaB signaling antigen processing and presentation negative regulation of interferon-beta production circadian regulation of gene expression response to cytokine NIK/NF-kappaB signaling myeloid dendritic cell differentiation T-helper 1 cell differentiation innate immune response positive regulation of transcription from RNA polymerase II promoter cellular response to osmotic stress regulation of transcription, DNA-templated transcription from RNA polymerase II promoter positive regulation of gene expression T-helper 1 type immune response negative regulation of transcription, DNA-templated

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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RelB Polyclonal Antibody

RelB Antibody (25027-1-AP) in ICC/IF

Product Details

25027-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Flow Cytometry (Flow)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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