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Invitrogen
Renin Polyclonal Antibody
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Renin Antibody (PA5-115834) in IHC (P)
Immunohistochemistry analysis of Renin in rat testis tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115834) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115834
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human REN(Accession P00797), corresponding to amino acid residues V206-F256.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2900468
Product Specific Information
Antibody detects endogenous levels of total Renin.
Target Information
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: angiotensin-forming enzyme; Angiotensinogenase; EC 3.4.23; EC 3.4.23.15; FLJ10761; Renin; renin 1 structural; renin precursor, renal
Gene Aliases: HNFJ2; RATRENAA; REN; Ren1; RENAA
UniProt ID: (Human) P00797, (Rat) P08424
Entrez Gene ID: (Human) 5972, (Rat) 24715
kidney development
mesonephros development
angiotensin maturation
renin-angiotensin regulation of aldosterone production
proteolysis
regulation of blood pressure
male gonad development
hormone-mediated signaling pathway
protein catabolic process
response to lipopolysaccharide
cellular response to drug
response to immobilization stress
drinking behavior
regulation of MAPK cascade
cell maturation
beta-amyloid metabolic process
response to cAMP
response to cGMP
regulation of blood volume by renin-angiotensin
establishment of blood-nerve barrier
response to organic substance
response to drug
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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