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Invitrogen
Renin Recombinant Rabbit Monoclonal Antibody (1)
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FIGURE: 1 / 1
Renin Antibody (MA5-29766) in IHC (P)
Immunohistochemical staining of mouse Renin 1 in mouse kidney with Renin Recombinant Rabbit Monoclonal Antibody (1) (Product # MA5-29766, 1:200, formalin-fixed paraffin embedded sections). Positive staining was localized to juxtaglomerular cell. Left panel: tissue incubated with primary antibody. Right panel: tissue incubated with mixture of primary antibody and antigen (recombinant protein).
Product Details
MA5-29766
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
1
Immunogen
Recombinant Mouse REN1 protein (Met1-Arg402)
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2785588
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Mouse REN1/Renin-1.
Target Information
Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Angiotensinogenase; aspartyl-protease; EC 3.4.23; EC 3.4.23.15; FLJ10761; Kidney renin; renin b; Renin-1
Gene Aliases: D19352; Ren; Ren-1; Ren-A; Ren1; Ren1c; Ren1d; Rn-1; Rnr
UniProt ID: (Mouse) P06281
Entrez Gene ID: (Mouse) 19701
kidney development
angiotensin maturation
regulation of blood volume by renin-angiotensin
renin-angiotensin regulation of aldosterone production
proteolysis
establishment of blood-nerve barrier
regulation of blood pressure
hormone-mediated signaling pathway
response to organic substance
response to drug
drinking behavior
regulation of MAPK cascade
cell maturation
response to cAMP
response to cGMP
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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