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Invitrogen
Reslizumab Humanized Recombinant Human Monoclonal Antibody
FIGURE: 1 / 1
Reslizumab Humanized Antibody (MA5-41868) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human IL5 protein expressed in CHO cells using a Reslizumab biosimilar monoclonal antibody (Product # MA5-41868). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
Product Details
MA5-41868
Product Specifications
Species Reactivity
Human
Host/Isotype
Human
/ IgG4
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Immunogen
Human IL5
Conjugate
Form
Liquid
Concentration
0.76 mg/mL
Purification
Protein A
Storage buffer
PBS, pH 7.4
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2911011
Product Specific Information
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
Target Information
Reslizumab (Sch 55700) is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. Reslizumab is effective in neutralizing the function of IL-5. Reslizumab inhibits IL-5-dependent cell proliferation, with an IC50 value of approximately 91. 1pM. Reslizumab has high binding affinity for human IL-5, with KD values of 109 pM and 4. 3 pM in the Biacore surface plasmon resonance and Kinetic Exclusion Assay, respectively.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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