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Invitrogen
Rotavirus Polyclonal Antibody
FIGURE: 1 / 2
Rotavirus Antibody (PA1-85845) in ICC/IF, IHC, IV
PLoS pathogens 2020 -
Fig 1 Intracellular neutralisation assay. (A) Images of rotavirus-infected cells following electroporation of anti-VP6 MAb. Rotavirus-infected cells were stained with sheep polyclonal anti-rotavirus antibody and subsequently Alexa-Fluor 488-conjugated anti-sheep Ig. Scale bar 200mum (B) Fluorescent foci in (A) captured on a Nikon Eclipse Ti microscope were quantified by NIS analysis software. (C) Confocal i... View More
Product Details
PA1-85845
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Virus
Published species
Virus
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Five serotypes of group A Rotavirus strains Wa (serotype I), DS-1 (serotype II), Ito (III), HOCHI (IV) and 69M (VIII)
Conjugate
Form
Liquid
Concentration
5 mg/mL
Purification
Protein G
Storage buffer
PBS
Contains
0.09% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_935332
Product Specific Information
PA1-85845 detects human rotavirus serotypes I, II, III, IV, and VIII.
Sheep anti Rotavirus antibody recognizes human rotavirus serotypes I, II, III, IV and VIII.
Target Information
Rotavirus is a double-stranded RNA virus in the family Reoviridae. Five species of rotavirus (A-E) cause disease in animals with species A being the most common in human. Within rotavirus A there are different strains, called serotypes, based on the dual classification system of two proteins on the surface of the virus. Six viral proteins (VPs), or structural proteins, form the virion and six non-structural proteins (NSPs) are expressed in infected cells. Rotavirus is the most common cause of severe diarrhoea among infants and young children. Rotavirus gastroenteritis is a mild to severe disease characterised by vomiting, watery diarrhoea, and low-grade fever, but still leads to hundreds of thousands of deaths each year in developing countries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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