Search Thermo Fisher Scientific
Search Thermo Fisher Scientific
FIGURE: 1 / 2
Recommended positive controls: A431, HeLa, HepG2.
Predicted reactivity: Mouse (96%), Rat (97%), Xenopus laevis (80%), Chicken (88%), Rhesus Monkey (100%), Bovine (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The Formin-like protein 1 (FRL1) gene encodes a formin-related protein which has been implicated in morphogenesis, cyokinesis, and cell polarity. Formins are a conserved class of proteins expressed in all eukaryotes and have one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain and one GBD/FH3 (Rho GTPase-binding / formin homology 3) domain. FRL1 is located in the cytoplasm and is highly expressed in the spleen, lymph node and bone marrow cells. FRL1 possibly has a role in the control of cell motility, survival of macrophages and cytoskeletal organization.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DRG family-regulatory protein 2; IH1; RWD domain-containing protein 1
Gene Aliases: 0710001K08Rik; 2610002D06Rik; 2700069A07Rik; CGI-24; DFRP2; IH1; PTD013; RWDD1
UniProt ID: (Human) Q9H446, (Mouse) Q9CQK7
Entrez Gene ID: (Human) 51389, (Mouse) 66521
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