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Invitrogen
S100A7 Polyclonal Antibody
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Product Details
PA5-75689
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues in Human S100A7.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.4
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2719417
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE).
Target Information
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Protein S100-A15A; Protein S100-A7; Protein S100-A7A; Psoriasin; psoriasin 1; S100 calcium binding protein A15; S100 calcium binding protein A7-like 1; S100 calcium-binding protein A15; S100 calcium-binding protein A15A; S100 calcium-binding protein A7; S100 calcium-binding protein A7 (psoriasin 1); S100 calcium-binding protein A7A
Gene Aliases: AY465109; Gm1020; PSOR1; S100a15; S100a15a; S100a17l1; S100A7; S100a7a; S100A7C; S100A7f; S100A7L1
UniProt ID: (Human) P31151, (Mouse) Q6S5I3
Entrez Gene ID: (Human) 6278, (Mouse) 381493
response to reactive oxygen species
angiogenesis
epidermis development
positive regulation of T cell chemotaxis
keratinocyte differentiation
response to lipopolysaccharide
innate immune response
defense response to Gram-negative bacterium
sequestering of metal ion
positive regulation of ERK1 and ERK2 cascade
positive regulation of granulocyte chemotaxis
positive regulation of monocyte chemotaxis
inflammatory response
cytokine metabolic process
positive chemotaxis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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